Gastrine 7 días

Composition: OMEPRAZOLE …………………………………….40.00 g APPLE ESSENCE ………………………..0.10 g INACTIVE INGREDIENTS q.s. ………………………100.00 g. INDICATIONS FOR USE GASTRINE is an antisecretory, antiulcer agent indicated for the treatment of esophagitis, erosive gastritis, gastroduodenal ulcers, and the prevention and treatment of gastric erosions caused by ulcerogenic drugs. DOSAGE: 4 mg/kg per day. This is equivalent to 1 gram of the product per 100 kilograms of body weight. One 31.5-gram syringe provides 7 doses for an average horse weighing 450 kilograms. Administer once daily, preferably in the morning before feeding. Administration for 28 consecutive days is recommended; The dose may then be reduced by half and continued for another 28 days to prevent the condition from recurring after remission. SYRINGE INSTRUCTIONS: Take the syringe and turn the screw until the dose indicated on the barrel is reached. (Each mark on the barrel corresponds to 1 daily dose for a 450-kg horse.) The animal’s mouth must be empty. Hold the syringe vertically to prevent spillage, then remove the cap . Position the syringe at the outer corner of the animal’s lip. Squeeze the syringe until the dose is fully dispensed, stopping when the screw thread reaches the end. The entire dose must be deposited at the base of the tongue, toward the back of the mouth. Keep the horse’s head raised for a few moments to encourage swallowing of the product. If any product is spilled, it is recommended to administer another dose BIAVAILABILITY AND PHARMACODYNAMICS: After administration, the product is absorbed in the intestine and widely distributed, bound to albumin and alpha-1 glycoprotein, but with higher concentrations in the gastric parietal secretory cells. Peak serum concentrations occur between 0.5 and 3.5 hours. Omeprazole is completely metabolized in the liver into various metabolites, which are excreted primarily in the urine and, to a lesser extent, in the bile and feces. GASTRINE is an inhibitor of gastric acid secretion. In an acidic environment, it is activated to sulfenamide, a derivative that irreversibly binds to the H+/K+ ATPase enzyme on the secretory surface of gastric parietal cells. From there, it inhibits the transport of hydrogen ions within the stomach. GASTRINE inhibits acid secretion under both basal and stimulated conditions, while also inhibiting the function of the hepatic cytochrome P-450 oxidative system. It may cause elevated liver enzymes. WARNINGS: Administer with caution in animals with liver disease. Verify that the product’s tamper-evident seal and storage conditions prior to use are appropriate, and that the product has not expired as indicated by the expiration date on the label. Verify that the product is administered exclusively via the route stated and approved herein. Do not exceed the doses recommended on the label. Do not administer to horses intended for human consumption. The recommended doses and warnings in all cases are subject to the discretion of the attending veterinarian. The proper storage temperature for this product is between 15 and 30°C, protected from direct sunlight and stored in a hygienic location. PACKAGING: Syringe containing 31.5 g / 7 DOSES